Leonard M. Miller Professor of Biochemistry and Molecular Biology
Professor and Vice-Chair for Research for the Department of Biochemistry and Molecular Biology
Primary Appointment of Biochemistry and Molecular Biology
Gautier Building Room #528E
Research Summary: Specific interests in Dr. Toboreks laboratory involve studies on the integrity of the blood-brain barrier (BBB) and how different pathological conditions can lead to the disruption and/or dysfunction of the BBB. Several projects are focused on HIV-1 trafficking into the brain. Another area of interest of Dr. Toboreks laboratory is connected to the effects of drugs of abuse on the brain endothelium. Molecular mechanisms of cerebrovascular toxicity induced by methamphetamine alone and in combination with HIV are studied both in in vitro and in vivo experimental setting.